This is such an exceptional product, that I felt it deserved it own page. Immune Ultra is a top notch protein formulation based on the latest research to boost the immune system. It offers new possibilities to people suffering from immune dysfunction, infections and most importantly - cancer.

Immune Ultra contains a mixture of whey protein isolate and concentrate to which bovine lactoferrin and alpha-lactalbumin have been added. It delivers 4.8 grams of lactoferrin and 4.1 grams of alpha-lactalbumin per serving, which is incredible. I have never found another product that has such a high level. Why is lactoferrin so important? Read on....

Lactoferrin:

Numerous studies have documented that lactoferrin is beneficial for the immune system, that it can prevent infections, and that it is an effective anti-cancer agent.

Lactoferrin appears to have a wide variety of uses in biological systems and is considered a first line immune defense in the human body. Though a natural component of cow's and human mother's milk, lactoferrin is found throughout the human body and occurs in all secretions that bathe mucous membranes such as saliva, tears, bronchial and nasal secretions, hepatic bile, pancreatic fluids, and is an essential factor in the immune response. Lactoferrin is concentrated in oral cavities where it will come in direct contact with pathogens (i.e. viruses, bacteria, etc.) and kills or greatly suppresses these pathogens through a variety of different mechanisms. (To fully explain would involve a LOT of chemistry, which for most..is a great cure for insomnia!).

Recent research has clearly demonstrated that lactoferrin can directly stimulate the immune system by increasing the production of cytokines and interleukins (your own body's biochemicals secreted to up-regulate various immune cells), activates natural killer cells (to kill anything which is not 'self') and helps your neutrophils and macrophages (central white blood cells and your personal 'army' of 'good guys').

Thanks to its immunostimulating effect, supplemental oral lactoferrin is effective against a broad range of tumours. Initial experimental animal studies showed that bovine lactoferrin significantly inhibits colon, esophagus, lung and bladder cancer cells from developing.

In one study, it was found that oral lactoferrin had an immunostimulating action at the level of the gut, inducing a body-wide anti-cancer effect. Supplementation resulted in a decrease in the rate of tumour growth in 6 out of 7 patients. Tumour growth was reduced from 33.3% before treatment to 9.9% after treatment with lactoferrin for a period of 2 months.

Lactoferricin is a peptide (small protein) which is obtained from the digestion of lactoferrin in hte stomach. Lactoferricin induces apoptosis (cell death) directly in several cancerous cell lines. More specifically, lactoferricin causes this cell death in human leukemia, lymphoma, breast, colon and ovarian cancer cells.

Studies in cell lines have also confirmed that alpha-lactalbumin can inhibit the growth of human cancer cells.

Preventing the Spread of Cancer

To spreac, cancer cells depend on the formation of new blood vessels so the tumour can grow. Lactoferrin is a potent inhibitor of blood vessel development and so prevents the progression and spread of tumours.

Lactoferrin and Intestinal Health

Lactoferrin appears to be particularly important in the health and function of the intestinal tract and has been found to greatly reduce systemic (body-wide) and intestinal inflammation in such conditions as inflammatory bowel disease and others. Animals subjected to a variety of pathogens known to cause both systemic and intestinal inflammation and damage show much greater resistance and reduced inflammation when fed lactoferrin. The gastrointestinal tract must be viewed as an ecologic system in which a balance between both good and bad bacterial flora (micro flora) exists. An overgrowth of bad bacteria in the intestinal tract is known to cause a wide range of sever problems that cause a myriad of pro-inflammatory mediators to be released, causing disruptions throughout the entire body.

When fed to adult animals and human infants, lactoferrin showed a dramatic increase in good micro flora—such as bifidus—and a decrease in bad bacteria, such as E. coli, streptococcus, clostridium and others. The result was desirable intestinal flora, which is known to be essential for optimal health, immunity and resistance to disease. An extensive review that examined the role of lactoferrin in inflammation and the health of the intestinal tract stated, “The possibility that lactoferrin limits the autodestructive inflammatory response presents a new alternative for the future management of systemic inflammation.”

Some research also suggests that lactoferrin is able to stimulate intestinal cell growth and may lead to better digestive functions, in addition to its ability to enhance the growth of “good” microflora in the intestine. There is little doubt that in addition to its immunomodulating effects, this natural peptide derived from whey has powerful pro-biotic properties.

Lactoferrin and Pathological Microorganisms

Iron is needed for bacterial growth. Lactoferrin sequesters iron - making it unavailable -which partly explains its antibacterial activity. Animal studies have clearly demonstrated that lactoferrin reduces bacterial proliferation, preventing bacterial overgrowth in the intestines and reducing bacterial numbers in infected organs. The addition of lactoferrin to the drinking water of animals with fungal infections promotes recovery.

Lactoferrin is also effective against viruses. Other than interferon, lactoferrin is the only agent capable of reducing the presence of the hepatitis C virus in chronic hepatitis C patients. Lactoferrin also has an antiviral effect against human papillomavirus, the causative factor behind most cervical cancer cases.

Lactoferrin directly inhibits viruses by binding to viral receptor sites, thus preventing the virus from infecting healthy cells. For example, in vitro studies have found that lactoferrin strongly binds to gp120 receptor on HIV-1 and HIV-2, resulting in inhibition of virus-cell fusion and entry of the virus into cells. In addition, lactoferrin indirectly kills or inhibits viruses by augmenting the systemic immune response to a viral invasion.

It’s interesting to note that there is a systemic deficiency of lactoferrin in people with HIV infection. One study that examined 22 asymptomatic and 45 symptomatic patients with HIV compared to 30 healthy controls found that “levels of plasma lactoferrin are decreased in HIV-1 infected patients in relation to the progression of the disease.” Another study found that the lack of lactoferrin (and secretory Iga) found in the oral cavities of people with HIV correlated strongly with the frequent infections in those areas often seen with patients with AIDS. Lactoferrin was also found to have “potent” anti-viral effects against the replication of both human HIV and cytomegalovirus (CMV) virus in several in vitro studies with no cytopathic effects on healthy cells.

In addition to HIV and CMV, additional studies have found that lactoferrin inhibits herpes simplex type 1 infection of healthy cells. The latter likely occurs by preventing viral attachment to healthy cells via the blocking of viral proteins and direct immune interactions with natural killer cells, lymphocytes and phagocytes.

Human and bovine lactoferrin share a similar structure, amino acid sequence and biological activity. Recent research has shown that bovine lactoferrin is in fact a more potent inhibitor of certain human viruses.

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